Arch.Pharm Res 2012;35(11):1945-1952. J Telemed Telecare. Int Immunopharmacol 2012;14(1):27-31. Planta Med 1991;57(2):119-121. Part 182 -- Substances Generally Recognized As Safe. View abstract. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. Barrella, M., Lauria, G., Quatrale, R., and Paolino, E. Hypokaliemic rhabdomyolysis associated with liquorice ingestion: report of an atypical case. Licorice that has had this substance removed (called DGL for deglycyrrhizinated licorice) may not have the same degree of side effects. This information may not fit your specific health circumstances. View abstract. Mechanisms by which Hange-shashin-to reduces prostaglandin E2 levels. View abstract. Benefits of licorice root: Uses, side effects, and more You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. View abstract. View abstract. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. is tatcha violet c brightening serum safe for pregnancy is tatcha violet c brightening serum safe for pregnancy Some believe it may also increase estrogen and prolactin levels in women, though more research is warranted. Tamir S, Eizenberg M, Somjen D, et al. Burgess, J. Severe hypokalemic paralysis and rhabdomyolysis due to ingestion of liquorice. B., and Zhang, Z. J. Gut 1978;19(9):779-782. One major reported side effect of licorice root is reduced levels of testosterone in men ( 10 ). Some research suggests that licorice extract may help kill bacteria in the mouth that cause tooth decay. It might also decrease the effects of birth control pills. ""- . It is often used together with peony, which can significantly enhance . It may disrupt the production of sex hormones ( 9 ). View abstract. Altern Med Rev 1999;4(3):178-188. Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine. Am J Chin Med 1996;24:165-8. Peony (Paeonia lactiflora) is an herb. Drugs & Vitamins . Fan ZJ, Liu JM, Li XX, et al. Evaluation of contextual and demographic factors on licorice effects on reducing hot flashes in postmenopause women. View abstract. View abstract. Medically reviewed by Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT By Kirsten Nunez on October 16, 2020. OTHER NAME(S): Acide Glycyrrhizique, Acide Glycyrrhizinique, Alca. Int Urol Nephrol. Traditionally, white peony root is used for treating a wide range of health ailments, like inflammation, pain, and many more. View abstract. View abstract. Izv Akad Nauk Ser Biol 1997;2:235-7. . Apparent mineralcorticoid excess syndrome, an often forgotten or unrecognized cause of hypokalemia and hypertension: case report and appraisal of the pathophysiology. A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema. Asian Medical Journal 1984;26(7):423-438. View abstract. Roussak NJ. View abstract. *. Liu J. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. View abstract. Alt Med Rev 2001;6:495-9. Am J Respir.Cell Mol.Biol. In Vivo 2021;35(4):2163-2169. View abstract. Cinatl J, Morgenstern B, Bauer G, et al. View abstract. Bronson Korean Panax Ginseng 1000 mg Supports Energy, Endurance & Vitality + Memory and Mental Performance, 120 Capsules. Okubo T, Nagai F, Seto T, et al. Licorice or Mulethi, also known as "Sweetwood", is an effective and potent medicinal herb. Health Care Women Int. West J Med 1997;167(3):184-185. View abstract. Int J Environ Res Public Health 2021;19(1):242. Jafari Z, Emtiazy M, Sohrabvand F, et al. View abstract. View abstract. A., van der Ven, P. F., Martin, M., Sherman, J., and Haley, J. Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin. A newly-filed federal lawsuit claims eating too much of The Hershey Company's Good & Plenty and black licorice Twizzlers candies can cause serious health problems, maybe even death. Phytomedicine 2003;10:271-85. Drug Metab Dispos 2015;43(7):1147-53. Hattori, T., Ikematsu, S., Koito, A., Matsushita, S., Maeda, Y., Hada, M., Fujimaki, M., and Takatsuki, K. Preliminary evidence for inhibitory effect of glycyrrhizin on HIV replication in patients with AIDS. It's not suggested to take St. John's wort if you take blood thinners. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . View abstract. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. Int J Dermatol 1999;38:387-92 . Effects of total glucosides of peony on immunological hepatic fibrosis in rats. Luper, S. A review of plants used in the treatment of liver disease: part two. Licorice root extract is often used to relieve symptoms of indigestion, such as acid reflux, upset stomach, and heartburn. . View abstract. Pulmonary edema following a licorice binge. Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. Farese RV Jr, Biglieri EG, Shackleton CH, et al. Gut 1969;10:299-302. View abstract. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. The anti-estrogenic action of beta-glycyrrhetinic acid. Licorice can decrease potassium levels. Peony (Paeonia spp). Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2013 Jun;19(4):227-8. 2020;50:102401. View abstract. Licorice might change how these pumps work and change how much medication stays in the body. Eur J Pharmacol 11-7-2005;524(1-3):111-119. Guo, D., Ye, G., and Guo, H. A new phenolic glycoside from Paeonia lactiflora. 2014 Jun;23(3):189-92. Am J Chin Med 2001;29(3-4):459-467. Int Immunopharmacol. In a 30-day study in 50 adults with indigestion, taking a 75-mg licorice . Mitscher, L. A., Park, Y. H., Clark, D., and Beal, J. L. Antimicrobial agents from higher plants. View abstract. J Clin Hypertens (Greenwich) 2008;10:153-7. Practitioner 1973;210:820-3. Kim YR, Nam SH. Antiviral Res 2003;59(1):41-47. View abstract. Some birth control pills contain estrogen. [Paeonia Lactiflora injection in treating chronic cor pulmonale with pulmonary hypertension]. View abstract. 1994;14:207-9, 195. . View abstract. According to research, the combination of . Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. View abstract. View abstract. View abstract. Herb-Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic Study in Rats. View abstract. Cochrane Database Syst Rev 2004;4:CD002291. Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancer. Chin J Integr Med 2022. One of its most known effects is the induction of hypertension, and it can induce what appears to be pseudohyperaldosteronism, due to glycyrrhetinic acid, the main active component of the root. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. Prospective study]. Chen, W. G. and Ba, Z. M. Prof. ZHANG Yi's experience in treating severe arrhythmia. View abstract. Biol Pharm Bull. Therapeutic Research Faculty 2020. J Hepatol 1994;21:601-9. Pakravan F, Salehabad NH, Karimi F, Isfahani MN. Phytother Res 2008;22(6):709-724. Awad N, Makar G, Burroughs V, Ravi P, Burroughs SR. Licorice-induced apparent mineralocorticoid excess causing persistent hypertension and hypokalemia. In an ovarietctomized model, oral administration of a combination of white peony and licorice increased DHEA and serum estrogen concentration. Lancet 2003;361:2045-6.. View abstract. Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. 2 in the perioperative stage of laparoscopic cholecystectomy]. View abstract. [Study on activating blood and eliminating stasis of total paeony glycoside(TPG)]. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Neth J Med 2005;63:146-8. Koo YK, Kim JM, Koo JY, et al. CJEM 2010;12(3):224-225. View abstract. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. Feng Z, Xu J, He G, et al. Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter). Pfeifer BL, Pirani JF, Hamann SR, Klippel KF. BMJ Case Rep 2012;2012. View abstract. Chin, Y. W., Jung, H. A., Liu, Y., Su, B. N., Castoro, J. Taking peony along with estrogen might increase the effects and side effects from estrogen. View abstract. Eur J Clin Pharmacol 2010;66(8):805-810. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. View abstract. Clin Pharmacol Ther 1996;59:62-71. Contact Dermatitis 1989; 20:152-3.. View abstract. Fujisawa, Y., Sakamoto, M., Matsushita, M., Fujita, T., and Nishioka, K. Glycyrrhizin inhibits the lytic pathway of complement--possible mechanism of its anti-inflammatory effect on liver cells in viral hepatitis. Licorice root and white peony for PCOS. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(12):1121-1123. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Peony: Uses, Side Effects, Dose, Health Benefits - EMedicineHealth Guo, T. L. and Zhou, X. W. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. Lee, C. K., Park, K. K., Lim, S. S., Park, J. H., and Chung, W. Y. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Li J, Fan X, Wang Q. Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: a case report. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Zong, P. P., Yan, T. Y., and Gong, M. M. [Clinical and experimental studies of effects of huayu decoction on scavenging free radicals]. Too much black licorice, the federal agency says, can lead to "abnormal heart rhythms, as well as high blood pressure, edema (swelling), lethargy, and congestive heart failure." . Celik, M. M., Karakus, A., Zeren, C., Demir, M., Bayarogullari, H., Duru, M., and Al, M. Licorice induced hypokalemia, edema, and thrombocytopenia. Gomaa AA, Mohamed HS, Abd-Ellatief RB, Gomaa MA, Hammam DS. Licorice has anti-acid and relieves the tension of gastrointestinal smooth muscle. View abstract. Best Male Enhancement Pills: Gaia Herbs Male Libido Review Ann Noninvasive Electrocardiol. Licorice Root Side Effects: 7 Ways It May Harm Your Health - STYLECRAZE View abstract. 10 Best Surasang Korean Ginseng Drinks - Of 2023 2019;33(1):117-29. Hyodo T, Taira T, Kumakura M, et al. Ann Pharmacother 2003;37(6):836-838. 2000;19(8):434-439. View abstract. View abstract. Life Sci 1993;53(5):PL63-8. View abstract. View abstract. This fragrant, perennial plant -- a member of the celery family -- has smooth purplish stems and umbrella-shaped clusters of white flowers and winged fruits in July and August. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Mattarello MJ, Karbowiak I, Ermolao A, and et al. G Ital Dermatol Venereol 2010;145(6):789-792. Acharya SK, Dasarathy S, Tandon A, et al. Objective: To evaluate the effect of different ratio of peony and licorice and Christina Loosestrife herb decoction on isolated in New Zealand . Brasseur, A. and Ducobu, J. Therapeutic Research Faculty 2020. Effect of peony and Licorice Decoction on New Zealand rabbits with Allergic contact dermatitis to Glycyrrhiza inflata root extract in an anti-acne cosmetic product. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. People who regularly take large amounts of licorice, more than 20 g/day, may raise blood levels of the hormone aldosterone, which can cause serious side effects, including headache, high blood pressure, and heart problems.
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